JTP10-△-R9 (TFA)
Product Specifications
UNSPSC Description
JTP10-△-R9 TFA is a selective JNK2 peptide inhibitor, with an IC50 of 89 nM, exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3[1].
Target Antigen
JNK
Type
Peptides
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jtp10-r9-tfa.html
Purity
99.41
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
O=C(CCCCCNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC([C@H]2N(CCC2)C(C)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O)CC3=CC=CC=C3)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N.OC(C(F)(F)F)=O
Molecular Weight
2860.31
References & Citations
[1]Tamer S. Kao, et al. Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration. ACS Chem Biol. 2011 Jun 17;6(6):658-66.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2247/JTP10-R9-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2247/JTP10-R9-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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