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Emicerfont

Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM.

Product Specifications

CAS Number

[786701-13-1]

Product Name Alternative

GW876008

UNSPSC

12352005

Target

CRFR

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Emicerfont.html

Purity

98.03

Smiles

CC1=CC(OC)=CC=C1N(CC2)C3=C2C(N4C=CC(N5CCN([H])C5=O)=N4)=CC(C)=N3

Molecular Formula

C22H24N6O2

Molecular Weight

404.46

References & Citations

[1]Zorrilla EP, et al. Behavioral, biological, and chemical perspectives on targeting CRF (1) receptor antagonists to treat alcoholism. Drug Alcohol Depend. 2013 Mar 1;128 (3) :175-86.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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