Clemastine (fumarate)
Clemastine (HS-592) fumarate is a selective histamine H1 receptor antagonist. Clemastine fumarate is an antihistamine mainly used for relieving symptoms of allergic reactions primarily by competing with histamine to bind H1 receptors. Anti-inflammatory effects[1][2].
Product Specifications
CAS Number
14976-57-9
Product Name Alternative
HS-592 (fumarate) ; Meclastine (fumarate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Clemastine-fumarate.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 11.67 mg/mL (ultrasonic) |H2O : 0.67 mg/mL (ultrasonic)
Smiles
CN1[C@@H](CCO[C@](C2=CC=CC=C2)(C3=CC=C(Cl)C=C3)C)CCC1.O=C(O)/C=C/C(O)=O
Molecular Formula
C25H30ClNO5
Molecular Weight
459.96
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor
Citation 01
Available Sizes
Frequently Asked Questions
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