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Cinobufaginol

Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μΜ and 1.270 μΜ for CNE-1 and CNE-2Z, respectively[1].

Product Specifications

CAS Number

6691-83-4

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cinobufaginol.html

Purity

99.75

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C=C1)OC=C1[C@H]2[C@@H](OC(C)=O)[C@@]3([H])[C@]4(O3)[C@]5([H])CC[C@]6([H])C[C@@H](O)CC[C@]6(CO)[C@@]5([H])CC[C@]24C

Molecular Formula

C26H34O7

Molecular Weight

458.54

References & Citations

[1]Liu JS, et al. Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolidesfrom toad venom. Fitoterapia. 2019 Apr;134:362-371.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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