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Taurocholic acid (sodium salt hydrate)

Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate) is a bile acid involved in the emulsification of fats.

Product Specifications

CAS Number

[345909-26-4]

Product Name Alternative

Sodium taurocholate hydrate; N-Choloyltaurine (sodium salt hydrate)

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Taurocholic-Acid-sodium-hydrate.html

Concentration

10mM

Purity

98.51

Solubility

DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : ≥ 100 mg/mL

Smiles

C[C@H](CCC(NCCS(=O)(O[Na])=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C.O

Molecular Formula

C26H46NNaO8S

Molecular Weight

555.70

Precautions

H315, H319, H335

References & Citations

[1]Mooranian A, et al. The effect of a tertiary bile acid, taurocholic acid, on the morphology and physical characteristics of microencapsulated probucol: potential applications in diabetes: a characterization study. Drug Deliv Transl Res. 2015 Oct;5 (5) :511-22.|[2]Mo J, Yang A, et al. Neuronostatin ameliorates sodium taurocholate-induced acute pancreatitis in rats. Dig Dis Sci. 2013 Oct;58 (10) :2903-7.|[3]Du D, Yao L, et al. Protective effects of flavonoids from Coreopsis tinctoria Nutt. on experimental acute pancreatitis via Nrf-2/ARE-mediated antioxidant pathways. J Ethnopharmacol. 2018 Oct 5;224:261-272.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite; Microbial Metabolite

Citation 01

Biomolecules. 2022 Jul 31;12 (8) :1063.|RSC Adv. 2018 8:8469-8483.|SSRN. 2022 Jan 26.|Adv Healthc Mater. 2024 Dec 4:e2402773.|FASEB J. 2022 May;36 (5) :e22305.|Int J Mol Sci. 2025 Feb 22;26 (5) :1899.|Microbiome. 2025 Jun 18;13 (1) :145.|Nat Commun. 2025 Aug 30;16 (1) :8124.|Proc Natl Acad Sci U S A. 2025 Dec 2;122 (48) :e2524436122.|Research Square Preprint. 2024 Feb 13.|Sci Rep. 2024 Oct 31;14 (1) :26216.|Adv Sci (Weinh) . 2025 Feb 3:e2411719.|Antiviral Res. 2019 Sep:169:104544.|Biochim Biophys Acta Mol Cell Biol Lipids. 2025 Oct 3;1871 (1) :159692.|Biomedicines. 2025 Apr 4;13 (4) :874.|Cell Death Discov. 2025 Jul 23;11 (1) :338.|Food Funct. 2024 Apr 11.|Food Funct. 2024 Sep 30;15 (19) :9916-9927.|Int Immunopharmacol. 2024 Dec 10:145:113739.|J Enzyme Inhib Med Chem. 2025 Dec;40 (1) :2501743.|J Pharm Biomed Anal. 2025 Jul 15:259:116760.|J Transl Med. 2024 Dec 20;22 (1) :1124.|Nature. 2025 Jul;643 (8070) :192-200.|Placenta. 2024 Mar 25:148:20-30.|Plant Commun. 2025 Jan 13;6 (1) :101181.|Poult Sci. 2025 Jun 25;104 (9) :105489.|Research (Wash D C) . 2022 Nov 2:2022:9784081.|Research Square Print. 2022 Aug.|Science. 2024 Mar 22;383 (6689) :eadj4591.

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