4-Thiouridine
4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m) RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1].
Product Specifications
CAS Number
[13957-31-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/4-thiouridine-a.html
Purity
99.68
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O=C(N1)N([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C=CC1=S
Molecular Formula
C9H12N2O5S
Molecular Weight
260.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Burger K, et al. 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response. RNA Biol. 2013 Oct;10 (10) :1623-30.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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