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Human CGRPR&RAMP1 Full Length Heterodimer Protein (VLP)

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Specifications

Background

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

This protein .

Accession Number

Q16602-1 (CGRPR) & O60894-1 (RAMP1)

Expression Region

Glu 23 - Asn 461 (CGRPR) & Cys 27 - Val 148 (RAMP1)

Host

HEK293

Target

CGRPR & RAMP1

Conjugation

Unconjugated

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.

Endotoxin

1.0 EU per μg

Bioactivity

Immobilized Human CGRPR&RAMP1 Full Length Heterodimer Protein (VLP) (Cat. No. CG1-H52P6) at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CGRPR antibody, human IgG with a linear range of 0.5-8 ng/mL (QC tested).

Format

Liquid

Buffer

PBS, Arginine, pH7.4

Additives

Trehalose

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

250ug*2

Host or Source

HEK293

Species

Human

Protein ID

Q16602-1 (CGRPR) & O60894-1 (RAMP1)

Preservative

Trehalose

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