Cianopramine
Cianopramine (Cyanimipramine) is a tricyclic antidepressant, and a potent inhibitor of neuronal serotonin (5-HT) uptake. Cianopramine blocks central and peripheral 5-HT receptors[1][2].
Product Specifications
CAS Number
66834-24-0
Product Name Alternative
Cyanimipramine; Ro 11-2465
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cianopramine.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C2C(N(CCCN(C)C)C3=CC=CC=C3CC2)=C1
Molecular Formula
C20H23N3
Molecular Weight
305.42
References & Citations
[1]Eichler HG, et al. Effect of cianopramine, a tricyclic antidepressant, on platelet serotonin uptake and peripheral adrenergic function. Clin Pharmacol Ther. 1984 Oct;36 (4) :542-5. |[2]Pawlowski L, et al. Ro 11-2465 (cyan-imipramine), citalopram and their N-desmethyl metabolites: effects on the uptake of 5-hydroxytryptamine and noradrenaline in vivo and related pharmacological activities. Psychopharmacology (Berl) . 1985;86 (1-2) :156-63.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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