Baloxavir marboxil

Baloxavir marboxil (S-033188) is a selective inhibitor of influenza cap-dependent endonuclease. Baloxavir marboxil, a potent antiviral agent, shows activity against influenza A and B virus[1].

Product Specifications

CAS Number

[1985606-14-1]

Product Name Alternative

S-033188; RG 6152

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/Baloxavir_marboxil.html

Purity

99.98

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

O=C(C=C1)C(OCOC(OC)=O)=C2N1N([C@H]3C4=CC=C(F)C(F)=C4CSC5=CC=CC=C35)[C@@]6([H])N(CCOC6)C2=O

Molecular Formula

C27H23F2N3O7S

Molecular Weight

571.55

Precautions

H302, H315, H319, H335

References & Citations

[1]Frederick G Hayden, et al. Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents. N Engl J Med. 2018 Sep 6;379 (10) :913-923.|[2]Hideyuki Ikematsu, et al. Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts. N Engl J Med. 2020 Jul 23;383 (4) :309-320.