(±) -Hexanoylcarnitine (chloride)

(±) -Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±) -Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin (HY-129458) and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways[1][2].

Product Specifications

CAS Number

[6920-35-0]

Product Name Alternative

DL-Hexanoylcarnitine (chloride)

UNSPSC

12352211

Hazard Statement

H302, H317

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/racemic-hexanoylcarnitine-chloride.html

Purity

98.0

Solubility

H2O : 250 mg/mL (ultrasonic)

Smiles

CCCCCC(OC(CC(O)=O)C[N+](C)(C)C)=O.[Cl-]

Molecular Formula

C13H26ClNO4

Molecular Weight

295.80

Precautions

H302, H317

References & Citations

[1]Scarale MG, et al. Circulating Metabolites Associate With and Improve the Prediction of All-Cause Mortality in Type 2 Diabetes. Diabetes. 2022 Jun 1;71 (6) :1363-1370. |[2]Obayashi H, et al. Plasma 2-hydroxyglutarate and hexanoylcarnitine levels are potential biomarkers for skeletal muscle toxicity in male Fischer 344 rats. J Toxicol Sci. 2017;42 (4) :385-396.