Dynamin inhibitory peptide

Dynamin inhibitory peptide competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide blocks the dopamine D3 effect on GABAA receptors[1].

Product Specifications

CAS Number

[251634-21-6]

UNSPSC

12352209

Target

Dynamin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dynamin-inhibitory-peptide.html

Purity

96.09

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(N)=O)N

Molecular Formula

C47H80N18O14

Molecular Weight

1121.25

References & Citations

[1]Guojun Chen, et al. Dopamine D3 receptors regulate GABAA receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens. J Neurosci. 2006 Mar 1;26 (9) :2513-21.