MrgprX2 antagonist-3

MrgprX2 antagonist-3 is an MrgprX2 antagonist extracted from patent WO2021092240A1, example E117. MrgprX2 antagonist-3 can be used for the research of inflammatory disorders of the skin[1].

Product Specifications

CAS Number

[2642174-19-2]

UNSPSC

12352005

Target

Mas-related G-protein-coupled Receptor (MRGPR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mrgprx2-antagonist-3.html

Concentration

10mM

Purity

99.73

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@H](O)CN(CC)C(NC1=NC=C(S1)CC2=CC(F)=CC=C2)=O

Molecular Formula

C16H20FN3O2S

Molecular Weight

337.41

References & Citations

[1]CEVIKBAS F, et, al. Mrgprx2 antagonists for the treatment of inflammatory disorders. WO2021092240A1.|[2]Porebski G, et, al. Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions. Front Immunol. 2018 Dec 20;9:3027.