Human LIGHT Protein

<strong>Human LIGHT Protein</strong>_x000D_ <strong>Catalog number:</strong> B2018511_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ~17 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> LIGHT_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Heo SK, Choi Y, Jeong YK, Ju LJ, Yu HM, Kim DK, Seo HJ, Lee YJ, Cheon J, Koh S, Min YJ, Noh EK, Jo JC. LIGHT (TNFSF14) enhances osteogenesis of human bone marrow-derived mesenchymal stem cells PLoS One. 2021 Feb 19;16(2):e0247368._x000D_ 2: Han M, Sun Y, Zhao W, Xiang G, Wang X, Jiang Z, Xue Z, Zhou W. Comprehensive characterization of TNFSF14/LIGHT with implications in prognosis and immunotherapy of human gliomas Front Immunol. 2022 Oct 20;13:1025286._x000D_ 3: Heo SK, Yu HM, Kim DK, Seo HJ, Shin Y, Kim SA, Kim M, Kim Y, Lee YJ, Noh EK, Jo JC. LIGHT (TNFSF14) promotes the differentiation of human bone marrow-derived mesenchymal stem cells into functional hepatocyte-like cells PLoS One. 2023 Aug 8;18(8):e0289798._x000D_ 4: Wu Y, Zhan S, Chen L, Sun M, Li M, Mou X, Zhang Z, Xu L, Xu Y. TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation J Transl Med. 2023 Aug 14;21(1):544._x000D_ 5: Lu H, Yang HL, Zhou WJ, Lai ZZ, Qiu XM, Fu Q, Zhao JY, Wang J, Li DJ, Li MQ. Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence Autophagy. 2021 Sep;17(9):2511-2527._x000D_ 6: Brunetti G, Storlino G, Oranger A, Colaianni G, Faienza MF, Ingravallo G, Di Comite M, Reseland JE, Celi M, Tarantino U, Passeri G, Ware CF, Grano M, Colucci S. LIGHT/TNFSF14 regulates estrogen deficiency-induced bone loss J Pathol. 2020 Apr;250(4):440-451._x000D_ 7: Heo SK, Noh EK, Gwon GD, Kim JY, Jo JC, Choi Y, Koh S, Baek JH, Min YJ, Kim H. LIGHT (TNFSF14) Increases the Survival and Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells PLoS One. 2016 Nov 11;11(11):e0166589._x000D_ 8: Celik S, Langer H, Stellos K, May AE, Shankar V, Kurz K, Katus HA, Gawaz MP, Dengler TJ. Platelet-associated LIGHT (TNFSF14) mediates adhesion of platelets to human vascular endothelium Thromb Haemost. 2007 Oct;98(4):798-805._x000D_ 9: Holmes TD, Wilson EB, Black EV, Benest AV, Vaz C, Tan B, Tanavde VM, Cook GP. Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):E5688-96._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31826304">10: Brunetti G, Belisario DC, Bortolotti S, Storlino G, Colaianni G, Faienza MF, Sanesi L, Alliod V, Buffoni L, Centini E, Voena C, Pulito R, Novello S, Ingravallo G, Rizzi R, Mori G, Reseland JE, Ware CF, Colucci S, Ferracini R, Grano M, Roato I. LIGHT/TNFSF14 Promotes Osteolytic Bone Metastases in Non-small Cell Lung Cancer Patients J Bone Miner Res. 2020 Apr;35(4):671-680. </a>_x000D_ _x000D_ <strong>Products Related to Human LIGHT Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>