(+) -TK216
(+) -TK216 is an enantiomer of TK216. TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor[1][2].
Product Specifications
CAS Number
1903783-77-6
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plus-tk216.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(C(Cl)=CC=C2Cl)C1(CC(C3=CC=C(C4CC4)C=C3)=O)O.[Rotation(+)]
Molecular Formula
C19H15Cl2NO3
Molecular Weight
376.23
References & Citations
[1]Spriano F, et al. The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents. Clin Cancer Res. 2019 Aug 15;25 (16) :5167-5176.|[2]Jean-Michael Vernier, et al. Indolinone compounds and uses thereof. WO2016057698A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR10331660 96 Well
Monkey Olfactory receptor 10S1 (OR10S1) ELISA Kit
Sign In for Pricing
View Details SPATA6-8622M 50 µg
Recombinant Mouse SPATA6 Protein, His (Fc)-Avi-tagged
Sign In for Pricing
View Details PDEH100928-01 20 µg
Recombinant Human TGF-beta 2/TGFB2 protein (His tag)
Sign In for Pricing
View Details PDEH100928-02 100 µg
Recombinant Human TGF-beta 2/TGFB2 protein (His tag)
Sign In for Pricing
View Details PDEH100928-03 500 µg
Recombinant Human TGF-beta 2/TGFB2 protein (His tag)
Sign In for Pricing
View Details