(+)-TK216
Product Specifications
UNSPSC Description
(+)-TK216 is an enantiomer of TK216 (HY-122903). TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor[1][2].
Target Antigen
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/plus-tk216.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(C(Cl)=CC=C2Cl)C1(CC(C3=CC=C(C4CC4)C=C3)=O)O.[Rotation (+)]
Molecular Weight
376.23
References & Citations
[1]Spriano F, et al. The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents. Clin Cancer Res. 2019 Aug 15;25(16):5167-5176.|[2]Jean-Michael Vernier, et al. Indolinone compounds and uses thereof. WO2016057698A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122903B/plus-TK216-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122903B/plus-TK216-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1903783-77-6
Available Sizes
Curated Selection
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