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Rabeprazole (sodium)

Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].

Product Specifications

CAS Number

117976-90-6

Product Name Alternative

LY307640 (sodium)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Bacterial; Proton Pump

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis; Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/Rabeprazole-sodium.html

Purity

99.9

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : ≥ 100 mg/mL

Smiles

O=S(C1=NC2=CC=CC=C2N1[Na])CC3=NC=CC(OCCCOC)=C3C

Molecular Formula

C18H20N3NaO3S

Molecular Weight

381.42

Precautions

H302, H315, H319, H335

References & Citations

Trichomonas Vaginalis

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Citation 01

Front Immunol. 2022 Jun 21;13:895869.|Nat Commun. 2023 Jul 14;14 (1) :4217.|Results Chem. 2024 Oct.

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