Rabeprazole (sodium)
Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].
Product Specifications
CAS Number
117976-90-6
Product Name Alternative
LY307640 (sodium)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Bacterial; Proton Pump
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Rabeprazole-sodium.html
Purity
99.9
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : ≥ 100 mg/mL
Smiles
O=S(C1=NC2=CC=CC=C2N1[Na])CC3=NC=CC(OCCCOC)=C3C
Molecular Formula
C18H20N3NaO3S
Molecular Weight
381.42
Precautions
H302, H315, H319, H335
References & Citations
Trichomonas Vaginalis
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Front Immunol. 2022 Jun 21;13:895869.|Nat Commun. 2023 Jul 14;14 (1) :4217.|Results Chem. 2024 Oct.
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