Human CCN1 Protein

<strong>Human CCN1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011851_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1.0 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Cyclin-I protein, CYC1 protein, CYI protein, CCN 1 protein, CCN-1 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Jun JI, Lau LF. The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing Nat Cell Biol. 2010 Jul;12(7):676-85._x000D_ 2: Hsu PL, Chen JS, Wang CY, Wu HL, Mo FE. Shear-Induced CCN1 Promotes Atheroprone Endothelial Phenotypes and Atherosclerosis Circulation. 2019 Jun 18;139(25):2877-2891._x000D_ 3: Kulkarni T, Kurundkar AR, Kim YI, de Andrade J, Luckhardt T, Thannickal VJ. The senescence-associated matricellular protein CCN1 in plasma of human subjects with idiopathic pulmonary fibrosis Respir Med. 2020 Jan;161:105821._x000D_ 4: Quan T, Xiang Y, Liu Y, Qin Z, Yang Y, Bou-Gharios G, Voorhees JJ, Dlugosz AA, Fisher GJ. Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging J Invest Dermatol. 2021 Apr;141(4S):1007-1016._x000D_ 5: Lee S, Ahad A, Luu M, Moon S, Caesar J, Cardoso WV, Grant MB, Chaqour B. CCN1-Yes-Associated Protein Feedback Loop Regulates Physiological and Pathological Angiogenesis Mol Cell Biol. 2019 Aug 27;39(18):e00107-19._x000D_ 6: Emre Y, Imhof BA. Matricellular protein CCN1/CYR61: a new player in inflammation and leukocyte trafficking Semin Immunopathol. 2014 Mar;36(2):253-9._x000D_ 7: Chen CC, Kim KH, Lau LF. The matricellular protein CCN1 suppresses hepatocarcinogenesis by inhibiting compensatory proliferation Oncogene. 2016 Mar 10;35(10):1314-23._x000D_ 8: Zhou Y, Li H, Liang X, Du H, Suo Y, Chen H, Liu W, Duan R, Huang X, Li Q. The CCN1 (CYR61) protein promotes skin growth by enhancing epithelial-mesenchymal transition during skin expansion J Cell Mol Med. 2020 Jan;24(2):1460-1473._x000D_ 9: Xie L, Song X, Lin H, Chen Z, Li Q, Guo T, Xu T, Su T, Xu M, Chang X, Wang LK, Liang B, Huang D. Aberrant activation of CYR61 enhancers in colorectal cancer development J Exp Clin Cancer Res. 2019 May 22;38(1):213._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/22566095">10: Quan T, Qin Z, Voorhees JJ, Fisher GJ. Cysteine-rich protein 61 (CCN1) mediates replicative senescence-associated aberrant collagen homeostasis in human skin fibroblasts J Cell Biochem. 2012 Sep;113(9):3011-8. </a>_x000D_ _x000D_ <strong>Products Related to Human CCN1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>