IL-21, Human

IL-21 Protein, Human is a class 1 cytokine, which is produced by activated CD4+ T cells. IL-21 Protein stimulation of T cells, B cells and NK cells leads to enhanced proliferation and mature effector function.

Product Specifications

Product Name Alternative

IL-21 Protein, Human, Human, E. coli

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-21-protein-human.html

Purity

96.00

Smiles

QDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS

Molecular Formula

59067 (Gene_ID) Q9HBE4-1 (Q32-S162) (Accession)

Molecular Weight

Approximately 15.4-18 kDa, based on SDS-PAGE under reducing conditions.

References & Citations

[1]Davis ID, et al. Clinical and biological efficacy of recombinant human interleukin-21 in patients with stage IV malignant melanoma without prior treatment: a phase IIa trial. Clin Cancer Res. 2009 Mar 15;15 (6) :2123-9.|[2]Steele N, et al. A phase 1 trial of recombinant human IL-21 in combination with cetuximab in patients with metastatic colorectal cancer. Br J Cancer. 2012 Feb 28;106 (5) :793-8.