IL-21, Human

Product Specifications

UNSPSC Description

IL-21 Protein, Human is a class 1 cytokine, which is produced by activated CD4+ T cells. IL-21 Protein stimulation of T cells, B cells and NK cells leads to enhanced proliferation and mature effector function.

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-21-protein-human.html

Purity

96.00

Smiles

QDRHMIRMRQ LIDIVDQLKN YVNDLVPEFL PAPEDVETNC EWSAFSCFQK AQLKSANTGN NERIINVSIK KLKRKPPSTN AGRRQKHRLT CPSCDSYEKK PPKEFLERFK SLLQKMIHQH LSSRTHGSED S

Molecular Weight

Approximately 15.4-18 kDa

References & Citations

[1]Davis ID, et al. Clinical and biological efficacy of recombinant human interleukin-21 in patients with stage IV malignant melanoma without prior treatment: a phase IIa trial. Clin Cancer Res. 2009 Mar 15;15(6):2123-9.|[2]Steele N, et al. A phase 1 trial of recombinant human IL-21 in combination with cetuximab in patients with metastatic colorectal cancer. Br J Cancer. 2012 Feb 28;106(5):793-8.