Lodenafil
Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED) [1].
Product Specifications
CAS Number
[139755-85-4]
Product Name Alternative
Hydroxyhomosildenafil
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/lodenafil.html
Purity
99.94
Solubility
DMSO : ≥ 250 mg/mL
Smiles
O=C1C2=C(NC(C3=CC(S(=O)(N4CCN(CC4)CCO)=O)=CC=C3OCC)=N1)C(CCC)=NN2C
Molecular Formula
C23H32N6O5S
Molecular Weight
504.60
Precautions
H302, H315, H319, H335
References & Citations
[1]Toque HA, et al. Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum. Eur J Pharmacol. 2008 Sep 4;591 (1-3) :189-95.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
PDE5
Available Sizes
Curated Selection
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