Picotamide

Picotamide is a combined inhibitor of thromboxane A2 (TxA2) synthase and receptor. Picotamide has antiplatelet activity. Picotamide promotes the reduction of microalbuminuria and the inhibition of growth of carotid plaques in diabetes. Picotamide can be used for researching acute or chronic cardiovascular diseases[1].

Product Specifications

CAS Number

[32828-81-2]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/picotamide.html

Purity

99.76

Solubility

DMSO : 5 mg/mL (ultrasonic; warming)

Smiles

O=C(C1=CC=C(OC)C(C(NCC2=CC=CN=C2)=O)=C1)NCC3=CC=CN=C3

Molecular Formula

C21H20N4O3

Molecular Weight

376.41

Precautions

H315, H319

References & Citations

[1]Celestini A, et al. A review of picotamide in the reduction of cardiovascular events in diabetic patients. Vasc Health Risk Manag. 2007;3 (1) :93-98.