2-Methylsuccinic acid

2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy.

Product Specifications

CAS Number

[498-21-5]

Product Name Alternative

Pyrotartaric acid

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-Methylsuccinic_acid.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(O)C(C)CC(O)=O

Molecular Formula

C5H8O4

Molecular Weight

132.12

Precautions

H315, H319, H335

References & Citations

[1]Grosso S, et al. Ethylmalonic encephalopathy: further clinical and neuroradiological characterization. J Neurol. 2002 Oct;249 (10) :1446-50.|[2]Nowaczyk MJ, et al. Ethylmalonic and methylsuccinic aciduria in ethylmalonic encephalopathy arise from abnormal isoleucine metabolism. Metabolism. 1998 Jul;47 (7) :836-9.