Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed)

Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 30000-70000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-90% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients[1].

Product Specifications

CAS Number

[9002-89-5]

Product Name Alternative

PVA (Mw 30000-70000, 87-90% hydrolyzed) ; Poly (Ethenol) (Mw 30000-70000, 87-90% hydrolyzed)

UNSPSC

12352200

Hazard Statement

H225-H301-H311-H331-H370-H371

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/polyvinyl-alcohol-mw-30000-70000-87-90-hydrolyzed.html

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

C=CO.[n]

Molecular Formula

(C2H4O) x

Molecular Weight

30000-70000 (Approximately)

Precautions

P210-P233-P240-P241-P242-P243-P260-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P330-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Elsherbiny DA, et al. Self-crosslinked polyvinyl alcohol/cellulose nanofibril cryogels loaded with synthesized aminophosphonates as antimicrobial wound dressings. J Mater Chem B. 2023 Aug 2;11 (30) :7144-7159.|[2]Rodwell DE, et al. Effects of polyvinyl alcohol administered in the diet to rats on fertility, early embryonic development, growth and development. Food Chem Toxicol. 2003 May;41 (5) :729-37. |[3]Sanders JM, et al. Vaginal absorption of polyvinyl alcohol in Fischer 344 rats. Hum Exp Toxicol. 1990 Mar;9 (2) :71-7.|[4]Patton TF, et al. Ocular evaluation of polyvinyl alcohol vehicle in rabbits. J Pharm Sci. 1975 Aug;64 (8) :1312-6.|[5]Carver MP, et al. Dose-response studies of gentamicin nephrotoxicity in rats with experimental renal dysfunction. II. Polyvinyl alcohol glomerulopathy. Toxicol Appl Pharmacol. 1985 Sep 15;80 (2) :264-73. doi: 10.1016/0041-008x (85) 90083-3.|[6]Alexandre N, et al. Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting--In vitro and in vivo studies. J Biomed Mater Res A. 2014 Dec;102 (12) :4262-75.|[7]Ting Y P, et al. Use of polyvinyl alcohol as a cell immobilization matrix for copper biosorption by yeast cells. Journal of Chemical Technology & Biotechnology: International Research in Process, Environmental & Clean Technology, 2000, 75 (7) : 541-546.|[8]Nishimura T, et al. Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion. Exp Hematol. 2019 Dec;80:16-20.