Aloesin
Aloesin (Aloeresin) is a tyrosinase inhibitor, and shows anti-inflammatory activity, ultraviolet protection, and antibacterium effects. Aloesin can induce apoptosis and be used in ovarian cancer research[1][2][3].
Product Specifications
CAS Number
30861-27-9
Product Name Alternative
Aloeresin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Tyrosinase
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aloesin.html
Purity
99.62
Solubility
DMSO : 270 mg/mL (ultrasonic)
Smiles
OC1=CC(C)=C(C(C=C(CC(C)=O)O2)=O)C2=C1[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)CO
Molecular Formula
C19H22O9
Molecular Weight
394.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang LQ, et al. Aloesin Suppresses Cell Growth and Metastasis in Ovarian Cancer SKOV3 Cells through the Inhibition of the MAPK Signaling Pathway. Anal Cell Pathol (Amst) . 2017;2017:8158254.|[2]Wahedi HM, et al. Aloesin from Aloe vera accelerates skin wound healing by modulating MAPK/Rho and Smad signaling pathways in vitro and in vivo. Phytomedicine. 2017 May 15;28:19-26.|[3]Y H Jin, et al. Aloesin and arbutin inhibit tyrosinase activity in a synergistic manner via a different action mechanism. Arch Pharm Res. 1999 Jun;22 (3) :232-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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