Lisuride (maleate)

Lisuride (maleate) is a potent agonist of dopamine with a probably direct action on dopaminergic receptors. Lisuride (maleate) is an ergot derivative. Lisuride (maleate) releases the premenstrual mastalgia without significant side effects[1][2].

Product Specifications

CAS Number

[19875-60-6]

UNSPSC

12352005

Hazard Statement

H300

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/lisuride-maleate.html

Purity

99.97

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC(/C=C\C(O)=O)=O.CN1[C@@]2([H])C(C3=CC=CC4=C3C(C2)=CN4)=C[C@@H](C1)NC(N(CC)CC)=O

Molecular Formula

C24H30N4O5

Molecular Weight

454.52

Precautions

H300

References & Citations

[1]Kaleli S, et al. Symptomatic treatment of premenstrual mastalgia in premenopausal women with lisuride maleate: a double-blind placebo-controlled randomized study. Fertil Steril. 2001;75 (4) :718-723. |[2]Horowski R, et al. Direct dopaminergic action of lisuride hydrogen maleate, an ergot derivative, in mice. Eur J Pharmacol. 1976;36 (2) :373-383.