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Tiotropium (bromide monohydrate)

Tiotropium bromide (BA-679 BR) monohydrate is a long-acting muscarinic receptor antagonist[1][2].

Product Specifications

CAS Number

411207-31-3

Product Name Alternative

BA-679 BR (monohydrate)

UNSPSC

12352005

Hazard Statement

H319, H336, H370

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tiotropium-bromide-monohydrate.html

Purity

99.68

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

[H][C@@]12[C@@H](O3)[C@@H]3[C@@](C[C@H](OC(C(C4=CC=CS4)(O)C5=CC=CS5)=O)C2)([H])[N+]1(C)C.O.[Br-]

Molecular Formula

C19H24BrNO5S2

Molecular Weight

490.43

Precautions

H319, H336, H370

References & Citations

[1]Barnes, P.J., et al., Tiotropium bromide (Ba 679 BR), a novel long-acting muscarinic antagonist for the treatment of obstructive airways disease. Life Sci, 1995. 56 (11-12) : p. 853-9.|[2]Hansel, T.T. and P.J. Barnes, Tiotropium bromide: a novel once-daily anticholinergic bronchodilator for the treatment of COPD. Drugs Today (Barc), 2002. 38 (9) : p. 585-600.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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