5α-Hydroxycostic acid
Product Specifications
UNSPSC Description
5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways[1].
Target Antigen
VEGFR
Type
Natural Products
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5α-hydroxycostic-acid.html
Purity
95.03
Solubility
10 mM in DMSO
Smiles
O[C@]12[C@@](CC[C@H](C1)C(C(O)=O)=C)(CCCC2=C)C
Molecular Weight
250.33
References & Citations
[1]Liang N, et, al. Two natural eudesmane-type sesquiterpenes from Laggera alata inhibit angiogenesis and suppress breast cancer cell migration through VEGF- and Angiopoietin 2-mediated signaling pathways. Int J Oncol. 2017 Jul;51(1):213-222.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2666/5α-Hydroxycostic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2666/5α-Hydroxycostic-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
132185-83-2
Available Sizes
Curated Selection
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