DOTA-ADIBO (TFA)
DOTA-ADIBO TFA is a DOTA-derived bifunctional chelator (BFC) that allows drug conjugation via an uncatalyzed, copper-free cycloaddition reaction. DOTA-ADIBO TFA enables the construction of fusion chelator systems that can be further used to synthesize radiotracers after Cu[64] modification. Positron emission tomography imaging of tumors expressing integrin αvβ6[1].
Product Specifications
UNSPSC
12352200
Target
Integrin
Type
Biochemical Assay Reagents
Related Pathways
Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dota-adibo-tfa.html
Purity
99.06
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(CN1CCN(CC(O)=O)CCN(CC(NCCC(N2C3=C(C#CC4=C(C2)C=CC=C4)C=CC=C3)=O)=O)CCN(CC(O)=O)CC1)=O.O=C(O)C(F)(F)F
Molecular Formula
C36H43F3N6O10
Molecular Weight
776.76
References & Citations
[1]Siow et al. Chemical Modifications on the αvβ6 Integrin Targeting A20FMDV2 Peptide: A Review[J]. ChemMedChem, 2024: e202400131.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
αvβ6
Available Sizes
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