M-PEG-NHS ester (MW 5000)
M-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[92451-01-9]
Product Name Alternative
MPEG-SC (MW 5000) ; mPEG-Succinimidyl ester (MW 5000)
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Biochemical Assay Reagents
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-peg-nhs-ester-mw-5000.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
COCCOCC(ON1C(CCC1=O)=O)=O.[n]
Molecular Formula
(C2H4O) nC7H9NO5
Molecular Weight
5000 (Average)
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; PEG Linkers
Available Sizes
Curated Selection
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