DS68591889
DS68591889 is a selective and orally active phosphatidylserine synthase 1 (PTDSS1) inhibitor. DS68591889 has no inhibitory activity against PTDSS2. DS68591889 induces the phospholipid imbalance in a wide range of cancer cells. DS68591889 negatively regulates B cell receptor (BCR) -induced Ca2+ signaling and subsequent apoptotic cell death. DS68591889 can be used for the cancer research, such as B cell lymphoma[1].
Product Specifications
CAS Number
[2488609-21-6]
UNSPSC
12352005
Target
Apoptosis; Phospholipase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ptdss1-in-1.html
Concentration
10mM
Purity
99.18
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C1OC2=C(C3=NNC4=C3C(C5=CC=C(C=C5)OC6=CC=C(C(C)=C6)OC(F)(F)F)N(CC(F)(C)F)C4=O)C=CC=C2N1
Molecular Formula
C29H21F5N4O5
Molecular Weight
600.49
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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