FITC Anti-Mouse CD172a/SIRPα Antibody[P84]
Selected Variant
E-AB-F1286C-01
Size: 50 Tests
Product Specifications
Background
CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.
Abbreviation
CD172a
Gene ID
19261
UniProt
Q64314
Host
Rat
Reactivity
Mouse
Target
BIT; CD172 antigen-like family member A; P84; PTPNS1; SHPS-1; SIRPα
Clonality
Monoclonal
Clone
P84
Conjugation
FITC
Applications
FCM
Field of Research
Cell Adhesion; Cell Biology; Immunology; Signal Transduction
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Rat IgG1, κ
Available Sizes
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