5 (6) -CFDA
5 (6) -CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes[1][2][3].
Product Specifications
CAS Number
124387-19-5
Product Name Alternative
5- (6) -Carboxyfluorescein diacetate; CFDA
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5_6_-CFDA.html
Purity
99.31
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(OC1=CC=C2C(OC3=C(C=CC(OC(C)=O)=C3)C24C5=CC(C(O)=O)=CC=C5C(O4)=O)=C1)=O.CC(OC6=CC=C7C(OC8=C(C=CC(OC(C)=O)=C8)C79C%10=CC=C(C(O)=O)C=C%10C(O9)=O)=C6)=O
Molecular Formula
C25H16O9
Molecular Weight
460.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Yang T, et al. A novel nonradioactive CFDA assay to monitor the cellular immune response in myeloid leukemia. Immunobiology. 2013 Apr;218 (4) :548-53.|[2]Card SD, et al. Assessment of fluorescein-based fluorescent dyes for tracing Neotyphodium endophytes in planta. Mycologia. 2013 Jan-Feb;105 (1) :221-9.|[3]Fang X, et al. Bone marrow-derived endothelial progenitor cells are involved in aneurysm repair in rabbits. J Clin Neurosci. 2012 Sep;19 (9) :1283-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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