Ganoderic acid B (Standard)
Product Specifications
UNSPSC Description
Ganoderic acid B (Standard) is the analytical standard of Ganoderic acid B. This product is intended for research and analytical applications. Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM)[1][2][3].
Target Antigen
EBV; HIV Protease
Type
Reference Standards
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ganoderic-acid-b-standard.html
Smiles
C[C@]([C@@]([C@]([C@H](C)CC(C[C@@H](C)C(O)=O)=O)([H])C1)(CC2=O)C)(C1=O)C([C@H](C[C@@]3([H])C4(C)C)O)=C2[C@]3(CC[C@@H]4O)C
Molecular Weight
516.67
References & Citations
[1]Zhou S, et al. Triterpenes and Soluble Polysaccharide Changes in Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), During Fruiting Growth. Int J Med Mushrooms. 2018;20(9):859-871.|[2]Zheng DS, et al. Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors. Exp Ther Med. 2017 Oct;14(4):3273-3278.|[3]el-Mekkawy S, et al. Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochemistry. 1998 Nov;49(6):1651-7.|[4]Shi J, et al. Ganoderic acid B attenuates LPS-induced lung injury. Int Immunopharmacol. 2020 Nov;88:106990.|[5]Koyama K, et al. Antinociceptive components of Ganoderma lucidum. Planta Med. 1997 Jun;63(3):224-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2006R/Ganoderic-acid-B-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2006R/
CAS Number
81907-61-1
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