Z-VDVAD-AFC
Product Specifications
UNSPSC Description
Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].
Target Antigen
Fluorescent Dye
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/z-vdvad-afc.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C(C1=CC=C(NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)C=C1O3)=CC3=O)F
Molecular Weight
862.80
References & Citations
[1]Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79.|[2]Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P4400/Z-VDVAD-AFC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P4400/
Clinical Information
No Development Reported
CAS Number
219138-08-6
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