Nafetolol
Nafetolol (K 5407), specifically effective on cardiac (β1) -adrenoceptors, is an orally active β blocking agent, with a t1/2 of ~ 2 h in dogs[1].
Product Specifications
CAS Number
42050-23-7
Product Name Alternative
K 5407 (free base)
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/nafetolol.html
Purity
98.24
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(CNC(C)(C)C)COC(C=C1)=C(C2CCC3CC2)C3=C1O
Molecular Formula
C19H29NO3
Molecular Weight
319.44
References & Citations
[1]G Goldaniga, et al. Pharmacokinetics and metabolism of a new beta-adrenergic blocking agent, the 1, ter-butyl-amino-3- (1,2,3,4-tetrahydro-1,4-ethano-8-hydroxy-5-naphthoxy) -2-propanol (K 5407) . Eur J Drug Metab Pharmacokinet. 1980;5 (1) :9-20.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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