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Anti-Mouse TNF-alpha/TNFSF2 Antibody (XT3.11)

Anti-Mouse TNF-alpha/TNFSF2 Antibody (XT3.11) is a rat-derived IgG1 antibody inhibitor, targeting to TNF-alpha/TNFSF2. Anti-Mouse TNF-alpha/TNFSF2 Antibody (XT3.11) neutralizes of TNF-alpha. Anti-Mouse TNF-alpha/TNFSF2 Antibody (XT3.11) can be used for the researches of cancer, infection and immunology, such as dengue virus and B16K1 tumor[1][2][3][4][5].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Dengue Virus; TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Anti-infection; Apoptosis

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-tnf-alpha-tnfsf2-antibody-xt3-11.html

Purity

95.00

Smiles

[Anti-MouseTNF-alpha/TNFSF2Antibody(XT3.11)]

Molecular Weight

(150 kDa)

References & Citations

[1]Kobayashi M, et al. TNF-α exacerbates SARS-CoV-2 infection by stimulating CXCL1 production from macrophages. PLoS Pathog. 2024 Dec 9;20 (12) :e1012776.|[2]Fowler AM, T et al. Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice. Cell Host Microbe. 2018 Nov 14;24 (5) :743-750.e5.|[3]Havell EA, et al. Endotoxin-induced tumor necrosis factor alpha synthesis in murine embryo fibroblasts. Infect Immun. 1993 May;61 (5) :1630-5.|[4]Katsumata K, et al. Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-α antibody in a murine model of rheumatoid arthritis. Arthritis Res Ther. 2019 Dec 23;21 (1) :298.|[5]Bertrand F, et al. TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma. Nat Commun. 2017 Dec 22;8 (1) :2256.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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