Tyk2-IN-19
Tyk2-IN-19 (Compound 1) is an orally active and blood-brain barrier (BBB) permeable Tyk2 inhibitor. Tyk2-IN-19 can be used for study of neurodegenerative diseases[1].
Product Specifications
CAS Number
[2866415-98-5]
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tyk2-in-19.html
Purity
98.62
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(CC)C1=C(NC2=C(OC)C(C3=NN(C)N=C3)=CC=N2)C=C(NC(C4CC4)=O)N=C1
Molecular Formula
C21H23N7O3
Molecular Weight
421.45
References & Citations
[1]Steven H. Spergel, et al. Substituted heterocyclic compounds. US20240124421A1. 2024-04-18.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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