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Isoetharine (mesylate)

Isoetharine (Isoetarine) mesylate is an orally active selective agonist of β-adrenergic receptors. Isoetharine mesylate is a catechol-like agent and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine mesylate can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2].

Product Specifications

CAS Number

7279-75-6

Product Name Alternative

Isoetarine (mesylate)

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/isoetharine-mesylate.html

Purity

99.05

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CS(=O)(O)=O.OC1=CC(C(O)C(NC(C)C)CC)=CC=C1O

Molecular Formula

C14H25NO6S

Molecular Weight

335.42

Precautions

H302, H312, H332

References & Citations

[1]Katsuhisa Kurogi, et al. Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs. Biochem Pharmacol. 2012 Nov 1;84 (9) :1186-95.|[2]Monika Maciag, et al. Evaluation of β-adrenergic ligands for development of pharmacological heart failure and transparency models in zebrafish. Toxicol Appl Pharmacol. 2022 Jan 1;434:115812.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

β adrenergic receptor

Available Sizes

Frequently Asked Questions

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