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Imidazoleacetic acid

Imidazoleacetic acid is an endogenous ligand that stimulates imidazole receptors.

Product Specifications

CAS Number

645-65-8

Product Name Alternative

Imidazolyl-4-acetic acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Imidazoleacetic_acid.html

Concentration

10mM

Purity

99.56

Solubility

DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : ≥ 200 mg/mL

Smiles

O=C(O)CC1=CN=CN1

Molecular Formula

C5H6N2O2

Molecular Weight

126.11

Precautions

H302, H315, H319, H335

References & Citations

[1]Prell GD, et al. Imidazoleacetic acid-ribotide: an endogenous ligand that stimulates imidazol (in) e receptors. Proc Natl Acad Sci U S A. 2004 Sep 14;101 (37) :13677-82.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite; Microbial Metabolite

Citation 01

FASEB J. 2022 May;36 (5) :e22305.|Nature. 2025 Jul;643 (8070) :192-200.|Nat Commun. 2025 Aug 11;16 (1) :7394.

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