KPU-300
KPU-300 (compound 6b) is a tubulin inhibitor. KPU-300 has potent cytotoxicity with an IC50 value of 7.0 nM against HT-29 cells[1].
Product Specifications
CAS Number
1620692-60-5
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kpu-300.html
Smiles
O=C(/C(NC/1=O)=C/C2=CC=CC(C(C3=CC=CC=C3)=O)=C2)NC1=C/C4=NC=CC=C4
Molecular Formula
C24H17N3O3
Molecular Weight
395.41
References & Citations
[1]Yoshiki Hayashi, et al. Development of a new benzophenone-diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure. ACS Med Chem Lett. 2014 Jul 23;5 (10) :1094-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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