DSPE-NHS

DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier[1].

Product Specifications

CAS Number

[1383932-86-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dspe-nhs.html

Purity

95.0

Solubility

DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C) |Methanol : 2 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(CCC(ON1C(CCC1=O)=O)=O)=O)(O)=O)=O

Molecular Formula

C49H89N2O13P

Molecular Weight

945.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Mikio Tatsutomi, et al. Preparation of a nitric oxide imaging agent from gelatin derivative micelles. Regen Ther. 2016 Sep 14;5:64-71.|[2]Kida A, et al. Cell surface-fluorescence immunosorbent assay for real-time detection of hybridomas with efficient antibody secretion at the single-cell level. Anal Chem. 2013 Feb 5;85 (3) :1753-9.