Dalbergioidin

Dalbergioidin, a well-known anthocyanin, ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway. Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM[1][2].

Product Specifications

CAS Number

[30368-42-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

TGF-beta/Smad

Type

Natural Products

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dalbergioidin.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C2=CC=C(O)C=C2O)COC3=CC(O)=CC(O)=C13

Molecular Formula

C15H12O6

Molecular Weight

288.25

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Seunghwa Baek, et al. Inhibitory effect of dalbergioidin isolated from the trunk of Lespedeza cyrtobotrya on melanin biosynthesis. J Microbiol Biotechnol. 2008 May;18 (5) :874-9.|[2]Xianguo Ren, et al. Dalbergioidin Ameliorates Doxorubicin-Induced Renal Fibrosis by Suppressing the TGF- β Signal Pathway. Mediators Inflamm. 2016;2016:5147571.