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Qc1

Qc1 is a reversible and noncompetitive threonine dehydrogenase (TDH) inhibitor. Qc1 can be used for the research of Metabolic disease[1][2].

Product Specifications

CAS Number

[403718-45-6]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Amino Acid Decarboxylase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/qc1.html

Purity

98.20

Solubility

DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC(NC(N2C3=CC=CC(C(F)(F)F)=C3)=S)=C(C=C1)C2=O)NCC4=CC=CC=C4

Molecular Formula

C23H16F3N3O2S

Molecular Weight

455.45

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Wang J, et al. Metabolic specialization of mouse embryonic stem cells. Cold Spring Harb Symp Quant Biol. 2011;76:183-193.|[2]Alexander PB, et al. Targeted killing of a mammalian cell based upon its specialized metabolic state. Proc Natl Acad Sci U S A. 2011;108 (38) :15828-15833.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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