HSP90-IN-32
HSP90-IN-32 is a Hsp90 C-terminal inhibitor that displays anti-proliferative activities against SKMel173, SKMel103, SKMel19 and A375 cells with IC50 values of 1.01 μM, 0.782 μM, 0.607 μM and 1.413 μM , respectively. HSP90-IN-32 is promising for research of anti-cancer agents[1].
Product Specifications
CAS Number
2169279-38-1
UNSPSC
12352211
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hsp90-in-32.html
Smiles
COC1=C(C2=CC(OC)=CC=C2)C=C(C=C1)C(N[C@H]3CC[C@H](C4=CC=C(C=C4)OC5CCN(CC5)C)CC3)=O
Molecular Formula
C33H40N2O4
Molecular Weight
528.68
References & Citations
[1]Blagg B, et al. The Investigation of Hsp90 C-terminal inhibitors containing Amide bioisosteres. ChemMedChem. 2024 Aug 17:e202400418.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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