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TCO-NHS Ester (axial)

TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

Product Specifications

CAS Number

[1610931-22-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/tco-nhs-ester-axial.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(OC1/C=C\CCCCC1)ON2C(CCC2=O)=O

Molecular Formula

C13H17NO5

Molecular Weight

267.28

Precautions

H302, H315, H319, H335

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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