ARG1-IN-1 (hydrochloride)

ARG1-IN-1 (example 1) hydrochloride is a human arginase 1 inhibitor with an IC50 of 29 nM[1].

Product Specifications

UNSPSC

12352005

Target

Arginase

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/arg1-in-1-hydrochloride.html

Purity

90.0

Solubility

10 mM in DMSO

Smiles

OB(O)CCC[C@H]1[C@@]2([H])[C@@](CNC2)([H])C[C@@]1(N)C(O)=O.[H]Cl

Molecular Formula

C11H22BClN2O4

Molecular Weight

292.57

References & Citations

[1]Mitcheltree MJ, et al. Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. ACS Med Chem Lett. 2020 Mar 23;11 (4) :582-588.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-98355AF488 0.1 mL

Rabbit Polyclonal Thimet Oligopeptidase/THOP1 Antibody [Alexa Fluor 488]

Ask

View Details

NBL1-07902 0.1 mg

SODD/BAG4 Overexpression Lysate (Native) - (Dry Ice)

Ask

View Details

UB-GEN-9778 100 µL

CV015 rabbit pAb

Ask

View Details

NBP2-47703AF750 0.1 mL

Mouse Monoclonal beta 2-Microglobulin Antibody (SPM617) [Alexa Fluor 750]

Ask

View Details