Cofrogliptin
Cofrogliptin (HSK7653) (compound 2), a tetrahydropyran derivative, is a potent oral dipeptidyl aminopeptidase 4 (DPP-4) inhibitor with Long-acting antidiabetic efficacy. Cofrogliptin (compound 2) has a great potential for type 2 diabetes mellitus (T2DM) [1].
Product Specifications
CAS Number
[1844874-26-5]
Product Name Alternative
HSK7653
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cofrogliptin.html
Purity
99.29
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)([C@@H](O[C@]1([H])C(C=C2F)=C(C=C2)F)[C@@](N(CC3=N4)CC3=CN4[S](C)(=O)=O)([H])C[C@@H]1N)F
Molecular Formula
C18H19F5N4O3S
Molecular Weight
466.43
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
DPP-4
Available Sizes
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