AS-1669058
AS-1669058 is a GPR119 agonist and a potential inhibitor of type 2 diabetes. AS-1669058 induces insulin secretion in response to high blood glucose levels in vitro and in vivo and increases insulin promoter activity. In animal studies, AS-1669058 improved glucose tolerance and reduced blood glucose levels in db/db mice[1].
Product Specifications
CAS Number
1395553-32-8
UNSPSC
12352005
Target
GPR119
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/as-1669058.html
Smiles
CC1=CC(NCCC2=C[N+]([O-])=CC=C2)=NC(C3=CC(F)=C(Br)C=C3F)=N1.O=C(O)C(O)=O
Molecular Formula
C20H17BrF2N4O5
Molecular Weight
511.27
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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