CK7

CK7, a Cdk2/9 inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367[1].

Product Specifications

CAS Number

[507487-89-0]

UNSPSC

12352005

Target

CDK; NEKs

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ck7.html

Concentration

10mM

Purity

99.72

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=[N+](C1=CC(NC2=NC=CC(C3=C(C)N=C(N)S3)=N2)=CC=C1)[O-]

Molecular Formula

C14H12N6O2S

Molecular Weight

328.35

References & Citations

[1]Pilakowski J, et al. Design, synthesis and biological evaluation of novel aminopyrazole- and 7-azaindole-based Nek1 inhibitors and their effects on zebrafish kidney development. Bioorg Med Chem Lett. 2021;53:128418.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK2; CDK9; NEK1

Available Sizes

Curated Selection

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