CK7
CK7, a Cdk2/9 inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367[1].
Product Specifications
CAS Number
[507487-89-0]
UNSPSC
12352005
Target
CDK; NEKs
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ck7.html
Concentration
10mM
Purity
99.72
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=[N+](C1=CC(NC2=NC=CC(C3=C(C)N=C(N)S3)=N2)=CC=C1)[O-]
Molecular Formula
C14H12N6O2S
Molecular Weight
328.35
References & Citations
[1]Pilakowski J, et al. Design, synthesis and biological evaluation of novel aminopyrazole- and 7-azaindole-based Nek1 inhibitors and their effects on zebrafish kidney development. Bioorg Med Chem Lett. 2021;53:128418.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2; CDK9; NEK1
Available Sizes
Curated Selection
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