Methylprednisolone succinate (sodium)

Methylprednisolone succinate (Methylprednisolone hydrogen succinate) sodium, a glucocorticoid, is a immunosuppressive agent with anti-inflammatory effects[1].

Product Specifications

CAS Number

[2375-03-3]

Product Name Alternative

Methylprednisolone hydrogen succinate (sodium)

UNSPSC

12352211

Hazard Statement

H351, H360

Target

Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/methylprednisolone-succinate-sodium.html

Purity

98.51

Solubility

DMSO : 116.67 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@](C(COC(CCC(O[Na])=O)=O)=O)(O)CC[C@@]1([H])[C@]3([H])C[C@H](C)C4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O

Molecular Formula

C26H33NaO8

Molecular Weight

496.53

Precautions

H351, H360

References & Citations

[1]Cheng S, Gao W, Xu X, et al. Methylprednisolone sodium succinate reduces BBB disruption and inflammation in a model mouse of intracranial haemorrhage. Brain Res Bull. 2016;127:226-233. |[2]J Mealey Jr, et al. Effects of dexamethasone and methylprednisolone on cell cultures of human glioblastomas. J Neurosurg. 1971 Mar;34 (3) :324-34.